PUBLICATIONS
代表性成果
实验室近年来在肿瘤基因组学、靶向治疗、表观遗传及抗病毒领域发表的研究论文与综述。
2025
ARTICLE
Genetic determinants of efficacy of antiviral drugs revealed by genome-wide CRISPR screens
DOI: 10.1016/j.antiviral.2025.106309
ARTICLE
STT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency
DOI: 10.1016/j.chembiol.2025.10.006
ARTICLE
A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
DOI: 10.1038/s41587-025-02793-8
ARTICLE
Catalytic-independent functions of Integrator/INTAC confer sensitivity to BET inhibition
DOI: 10.1038/s41589-024-01820-0
2020
2019
2015
ARTICLE
A DNA/HDAC dual-targeting drug with significantly enhanced anticancer potency
DOI: 10.15252/emmm.201404580
ARTICLE
A novel recurrent CHEK2 Y390C mutation identified in high-risk Chinese breast cancer patients impairs its activity and is associated with increased breast cancer risk
DOI: 10.1038/onc.2014.443